DOI: 10.1039/d6ra06069b ISSN: 2046-2069

Coumarin derivatives as promising anticancer drugs: a comprehensive review from synthesis to anticancer applications

Andi Suo, Mengjia Xu, Ming Yang, Zoran Marković, Hesham R. El-Seedi, Mingquan Guo

This review covers the synthesis and biological evaluation of coumarin derivatives, summarizing classical and modern synthetic strategies, structure–activity relationships, and anticancer mechanisms.