DOI: 10.1039/d3nj02685j ISSN:
Cooperative assistance of a sulfonamide in a proline-mediated direct asymmetric aldol addition
Kiran Kumari, Meeta Bhati, Roopendra Singh Madhukar, Akram Gulam Hussain Khan, Prachi Janjani, S. Rajagopala Reddy, Srinivasan Easwar- Materials Chemistry
- General Chemistry
- Catalysis
A sulfonamide moiety was introduced at the C-4 position of proline, cis to the –COOH group, to examine a possible synergistic interaction between the two groups and the consequent influence on the enamine mediated asymmetric aldol reaction.