DOI: 10.1039/d6np00031b ISSN: 0265-0568
Construction of cell factories, and multi-enzymatic and chemoenzymatic cascades to enable the efficient production of alkaloids
Zhenbo Yuan, Huiling Liu, Fei Li, Qingli Xiong, Shuaiju Liu, Yue Gao, Yijian RaoThis review summarizes alkaloid bioproduction through de novo biosynthesis, multi-enzymatic cascades, and chemoenzymatic strategies, and discusses current advances, bottlenecks, and future perspectives.