Comparison of N-butyl 2-cyanoacrylate glue fixation versus conventional suture fixation of polypropylene mesh for postoperative groin pain in patients undergoing Lichtenstein repair for inguinal hernia: A randomized clinical trial
Syed Arif, Rubik Ray, Tridip Dutta Baruah, Dharmendra DugarAbstract
INTRODUCTION:
A significant complication of inguinal hernia repair is chronic postoperative groin pain, which may be influenced by the method of mesh fixation. This randomized controlled trial was conducted with the objective of comparing the efficacy of N-butyl-2-cyanoacrylate (NBCA) glue fixation with conventional suture fixation of polypropylene mesh in Lichtenstein repairs.
MATERIALS AND METHODS:
This clinical trial enrolled 60 patients with unilateral, uncomplicated inguinal hernias. Participants were randomly allocated to either the suture fixation group (Group A) or the glue fixation group (Group B). The primary outcome, which included postoperative pain, was recorded at 24 h and at 7 days, 15 days, 30 days, and 90 days. The secondary outcomes included mesh fixation time, postoperative complications, and short-term recurrence.
RESULTS:
The mean mesh fixation time was significantly shorter in the glue group, at 4.5 min, than 13.63 min in the suture group (
CONCLUSION:
NBCA glue fixation constitutes a safe and effective alternative to conventional suture fixation for polypropylene mesh in Lichtenstein hernia repair. This method demonstrably reduces both postoperative pain and operative time without elevating the risk of complications or early recurrence. Consequently, this patient-friendly advancement merits serious consideration for broader clinical adoption.
CTRI REGISTRATION NUMBER:
CTRI/2024/11/077136.