DOI: 10.1097/rlu.0000000000005143 ISSN: 1536-0229

Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

Xue Zhu, Donghui Pan, Zhengwei Zhang, Ke Wang, Wenjun Zou
  • Radiology, Nuclear Medicine and imaging
  • General Medicine


Uveal melanoma is the most common intraocular malignancy in adults with a high rate of metastasis and mortality. This study presented the PET/CT imaging of 18F-AlF-NOTA-PRGD2 and 18F-FDG in a patient with primary uveal melanoma. In addition to fundus photograph and ophthalmic ultrasonography, both 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT imaging showed increased radioactive uptake in the lesions within the scan area. The tumoral lesions presented significantly higher uptake of 18F-AlF-NOTA-PRGD2 compared with that of 18F-FDG.

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