Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

Abstract

Uveal melanoma is the most common intraocular malignancy in adults with a high rate of metastasis and mortality. This study presented the PET/CT imaging of ¹⁸F-AlF-NOTA-PRGD2 and ¹⁸F-FDG in a patient with primary uveal melanoma. In addition to fundus photograph and ophthalmic ultrasonography, both ¹⁸F-AlF-NOTA-PRGD2 and ¹⁸F-FDG PET/CT imaging showed increased radioactive uptake in the lesions within the scan area. The tumoral lesions presented significantly higher uptake of ¹⁸F-AlF-NOTA-PRGD2 compared with that of ¹⁸F-FDG.