DOI: 10.4103/dljo.dljo_145_25 ISSN: 0972-0200

Comparative Study between Effectiveness and Safety of Fibrin Glue versus Vicryl Suture (8-0) in Limboconjunctival Autograft in Management of Primary Pterygium in a Tertiary Care Center

Supriya Gopichand Dange, Anup Vijay Shah, Amit Anantrao Deshmukh
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Abstract

Background:

Pterygium is a common ocular surface disorder, often managed surgically using conjunctival autografting. Fibrin glue and Vicryl sutures are the primary fixation methods, each with distinct advantages. This study compares their effectiveness, safety, and patient comfort.

Subjects and Methods:

A prospective, comparative study was conducted on 120 eyes with primary pterygium. Patients were randomized into two groups: fibrin glue ( n = 60) and Vicryl suture ( n = 60). Parameters assessed included operative time, postoperative complications, visual acuity, astigmatism, graft stability, and patient discomfort over follow-up at 1, 3, and 6 weeks.

Results:

The mean operative time was significantly lower in the fibrin glue group (16.62 ± 3.49 min) compared to Vicryl suture (39.55 ± 4.07 min, P < 0.001). Early postoperative complications were fewer in the fibrin glue group ( P < 0.001). Visual recovery was significantly faster in the fibrin glue group at the second follow-up ( P = 0.0005). No significant difference in astigmatism change or late complications was observed. Patient discomfort scores were consistently lower in the fibrin glue group across all follow-ups ( P < 0.05).

Conclusion:

Fibrin glue offers shorter surgical time, improved early postoperative comfort, and comparable safety to Vicryl sutures, making it a preferred choice for conjunctival autograft fixation in primary pterygium surgery.

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