DOI: 10.1039/d6ra05006a ISSN: 2046-2069

Comparative review of glycated albumin detection from conventional colorimetric assays to Raman spectroscopy, surface-enhanced Raman scattering, and surface plasmon resonance

L. A. S. P. Jayasekara, S. P. N. N. Senadeera, L. M Samarathunga, P. R. T. D. Priyashantha, D. U. Kottahachchi, C. B. Ranaweera

This review evaluates the shift from colorimetric NBT to RS, SERS, and SPR for glycated albumin detection. It demonstrates how reagent-free optical techniques offer enhanced specificity and real time monitoring, essential for clinical diagnostics.