Comparative Evaluation of the Effects of Two Distinct Matrix Metalloproteinase-inhibiting Irrigation Solutions, namely Chlorhexidine and Arabica Coffee Bean Extract (Coffea Arabica) on Fracture Resistance of Root-filled Teeth: An In vitro Study
Srikanth Pasari, Akilan Balasubramanian, Vala Vikram Kumar, Ali Aedh Hussain Alqahtani, C. H. Sumalatha, Meenakumari Chikkanna, J. Suresh Babu, C. Swarnalatha, Abhishek Singh NayyarBackground and Aim:
A plethora of studies have analyzed the effects of various irrigation solutions on the structure of dentin. However, the effects of these solutions on the signaling molecules present in the extracellular collagen matrix of dentin remain unclear. The aim of the present study was to compare the effects of two distinct matrix metalloproteinase-inhibiting irrigation solutions, namely, chlorhexidine (CHX) and Arabica coffee bean extract (Coffea arabica), on the fracture resistance of root-filled teeth.
Materials and Methods:
For the present study, 30 single-rooted teeth were selected, while they were divided into three groups based on the various irrigation solutions used, including Group I (CHX group), Group II (Coffea arabica group), and Group III (control group). After instrumentation and irrigation with the intended irrigation solution to be used, all the canals were restored using the single cone technique with
Results:
Highest mean fracture resistance values were recorded for Group III specimens (933.00 ± 25.84 Mpa) followed by Group II specimens (851.00 ± 28.46 Mpa), while least values were recorded for Group I specimens (732.00 ± 23.48 Mpa), with the results being statistically highly significant on intragroup and intergroup comparisons (
Conclusions:
Based on the results obtained, it was concluded that the use of Arabica coffee bean extract (Coffea arabica) as an irrigant comes out to be more promising than CHX in terms of the fracture resistance of root-filled teeth when considering long-term sequel of endodontic treatment.