Comparative Analysis of Inflammatory Tissue Responses in Patients with Metal-Based and Ceramic-based Dental Prostheses
Sangeetha Ramu, Pranjali Dutt, Ramanpal Singh Makkad, Navodita Jamwal, Miral Mehta, Subhash Chandra Pankaj, Nidhi MomayaAbstract
Introduction:
The selection of restorative materials for fixed dental prostheses significantly influences peri-prosthetic tissue health and long-term treatment success. Metal-based prostheses have been extensively used for decades; however, concerns regarding metal ion release and potential inflammatory responses have prompted increased interest in all-ceramic alternatives. Understanding the comparative inflammatory tissue responses between these material types is essential for evidence-based clinical decision-making.
Materials and Methods:
This prospective comparative clinical study evaluated inflammatory tissue responses in 120 patients receiving fixed dental prostheses, allocated to either metal-ceramic restorations (Group A,
Results:
Metal-ceramic restorations demonstrated significantly higher inflammatory biomarker concentrations at 12 months, with IL-1β levels of 142.6 ± 48.3 pg/mL compared to 82.4 ± 34.6 pg/mL in all-ceramic restorations (
Conclusion:
All-ceramic zirconia-based dental prostheses demonstrate superior biocompatibility with significantly reduced inflammatory tissue responses compared to metal-ceramic restorations, supporting their preferential use in patients seeking optimal peri-prosthetic tissue health.