DOI: 10.1093/femsle/fnag128 ISSN: 0378-1097
Community-Acquired Infection Caused by mcr-1 and bla OXA-48-Producing Escherichia coli : A Case Highlighting
Basma Mnif, Nizar KardounAbstract
Selective antimicrobial susceptibility supports antimicrobial stewardship strategy but may have limitations in high-resistance prevalence settings. We report a community-acquired infection of necrotic metastatic inguinal lymphadenopathy caused by two mcr-producing Escherichia coli isolates, including one blaOXA-48 producer. Initial selective susceptibility testing delayed recognition of clinically relevant resistance. This case highlights the risk of silent community dissemination of high-priority resistance determinants. It underscores the need for context-adapted susceptibility reporting to balance antimicrobial stewardship and resistance surveillance.