Comment on: Use of intracameral antibiotics prophylaxis in patients with posterior capsule rupture during cataract surgery: systemic review and meta-analysis.

A valuable meta-analysis was performed by the authors to investigate the prophylactic efficacy of several antibiotics to prevent postoperative endophthalmitis (PE) in case of a posterior capsule rupture (PCR) during cataract surgery.

It is of interest that the authors found a superior effect of moxifloxacin in the reduction of the incidence of endophthalmitis in the event of a PCR. This in addition to the better safety profile could make a call for preference of this antibiotic for use as antibiotic intra-ocular prophylaxis during cataract surgery. The authors also argue that there are arguments to use intra-ocular antibiotic prophylaxis only in case of a PCR, which is in line with data we published on this subject.