DOI: 10.4103/hjum.hjum_152_25 ISSN: 0974-1291

Clinical Validation of Unani Pharmacopoeial Formulation “Iṭrīfal Shahtara and Sharbat Unnab” in Cases of Buthūr (Macules/Pustules)

Mohammed Sheeraz Mushtaque Ahmad, Mohammad Zakir, Narendra Singh, Noor Zaheer Ahmad, Mohd Afsahul Kalam, Arjumand Shah, Andleeb Razaq

Abstract

Background:

Buthūr (macules/pustules) are a common symptom of many skin diseases, often causing social distress. These skin alterations require effective treatment, but a safe and proven cure has not yet been found. Ongoing research aims to develop natural, low-side-effect, cost-effective, and widely accepted treatments. The Unani System of Medicine, with its centuries-old therapeutic remedies, offers potential solutions. This study aimed to validate two Unani formulations – Iṭrīfal Shāhtara and Sharbat ‘Unnāb – which are commonly used for treating Buthūr but lack scientific validation.

Materials and Methods:

The study was conducted at the Regional Research Institute of Unani Medicine, Bhadrak, Odisha, involving 103 patients. Iṭrīfal Shāhtara (5 g) was administered orally with water twice a day, while Sharbat ‘Unnāb (20 ml) was given similarly for 21 days. Clinical assessments were made at baseline and on days 7, 14, and 21 using a Visual Analog Scale (VAS).

Results:

Both formulations provided relief in 91.26% of cases, with significant clinical improvement and changes in VAS score. Statistical analysis showed a significant difference at the 5% level using one-way analysis of variance.

Conclusion:

The study concludes that the drugs Iṭrīfal Shāhtara and Sharbat ‘Unnāb are effective in treating Buthūr , improving symptoms without side effects. The treatments were well tolerated, and no adverse effects were observed during the study.

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