DOI: 10.25259/kjs_32_2025 ISSN: 3066-6732

Clinical Significance of the Neutrophil-Lymphocyte Ratio as a Prognostic Marker for Adverse Outcomes in Patients with Acute Pancreatitis

Adarsh V. Honnalli, Patil Virupaxagouda

Objectives:

To evaluate the prognostic value of the neutrophil–lymphocyte ratio (NLR) in patients with acute pancreatitis and to determine its usefulness in predicting disease severity and adverse outcomes.

Material and Methods:

A prospective cross-sectional study including 50 patients diagnosed with acute pancreatitis. NLR was calculated on day 0, day 1, and day 2 and compared across CT severity groups. Statistical analysis was performed using ANOVA and chi-square tests.

Results:

NLR declined in mild and moderate cases but increased significantly in severe cases. The difference among groups was statistically highly significant (P < 0.01). Higher NLR was associated with longer hospital stay and organ dysfunction.

Conclusion:

NLR is a simple, cost-effective and reliable marker for early assessment of severity and prognosis in acute pancreatitis.

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