Clinical Practice Recommendations for Antithrombotic Management of Peripheral Artery Disease: An Indian Perspective
Paresh Pai, Varinder S Bedi, Dhanesh R. Kamerkar, Robbie George, Kumud M Rai, P C Gupta, Raghuram Sekhar, Venugopal Balaji, Rajiv Parakh, S.R. Subramanian, Vijay Thakore, Tapish Sahu, Ravul Jindal- General Medicine
Abstract
Currently, there are no guidelines or consensus recommendations on the antithrombotic management of peripheral artery disease (PAD) from an Indian perspective. In this article, we have summarized clinical practice recommendations on antithrombotic management of (i) asymptomatic chronic PAD (cPAD), (ii) symptomatic cPAD (intermittent claudication [IC] and chronic limb-threatening ischemia [CLTI]), and (iii) after revascularization (endovascular and surgical). An electronic search of the PubMed database was undertaken to identify relevant articles. Various combinations of keywords such as PAD, chronic peripheral arterial disease, asymptomatic chronic peripheral arterial disease, symptomatic chronic peripheral arterial disease, dual antiplatelet therapy, single antiplatelet therapy, dual pathway inhibition, antithrombotic, revascularization, endovascular, and surgical were used. Randomized controlled trials, case reports, practice guidelines, systematic literature reviews, and meta-analyses were screened and assessed. A roundtable meeting of experts (