Clinical Course of Suspected Hashitoxicosis with Korean Medicine: A Case Report

Objectives: Hashitoxicosis is a transient hyperthyroid phase that occurs during autoimmune thyroiditis, particularly Hashimoto’s thyroiditis. Because it results from the destructive release of thyroid hormones rather than increased hormone synthesis, optimal treatment strategies remain unclear.Methods: A 23-year-old woman with hyperthyroidism and suspected Hashitoxicosis was treated with <i>Ahnjeonbaekho-tang</i> and Ahnjeonbaekho-hwan for 3 months. Thyroid function tests, thyroid autoantibodies, and liver function tests were monitored.Results: During the observation period at our clinic, serum triiodothyronine (T3) and free thyroxine (T4) levels remained within the reference ranges. Thyroid-stimulating hormone increased from <0.03 mIU/L to 11.24 mIU/L and gradually decreased to 5.00 mIU/L. This pattern may reflect recovery of hypothalamic–pituitary–thyroid axis homeostasis during the course of suspected Hashitoxicosis. However, the possibility of natural disease progression cannot be excluded. Liver enzyme levels remained stable without significant elevation.Conclusions: These findings suggest that the treatment may be associated with stable thyroid function and preserved liver safety in patients with suspected Hashitoxicosis, highlighting the importance of careful differential diagnosis in cases of thyrotoxicosis.