Clinical Characteristics and Prognosis of Paediatric Chronic Inducible Urticaria: A Retrospective Study
Özgen Soyöz, Figen Ç. Çelik, Mehmet Ş. Kaya, İdil A. Hacı, İlke Taşkırdı, Canan Ş. Karkıner, Özlem Sancaklı, Demet CanAbstract
Background:
Chronic inducible urticaria (CIndU) is rare in children, with limited data available about its clinical features and prognostic factors.
Aims:
This study aimed to evaluate the clinical characteristics, subtype distribution, and prognosis of paediatric CIndU in a Turkish cohort.
Methods:
A retrospective analysis was conducted on 60 paediatric patients diagnosed with CIndU between 2019 and 2020 at a tertiary hospital. Data were collected on demographics, subtypes, comorbidities, treatments, and outcomes. Multivariate logistic regression was used to identify factors associated with non-remission. Statistical analyses included t-tests, Mann–Whitney U tests, and Kruskal–Wallis tests (
Results:
Symptomatic dermographism was the most common subtype (54%), followed by cold urticaria and cholinergic urticaria (13% each). Females predominated (55%), with symptomatic dermographism significantly more common in females (71.9%,
Conclusion:
Paediatric CIndU is heterogeneous, with symptomatic dermographism being the most common and least severe subtype. Atopy is a significant predictor of persistent disease, contrasting with some research in the literature but supported by recent studies. Larger studies are needed to validate these findings.