DOI: 10.47582/jompac.1999253 ISSN: 2717-7505

Clinical and laboratory factors associated with placental abruption: a retrospective case-control study

Rıfat Taner Aksoy, Aytekin Tokmak
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Aims: Placental abruption (PA) is a major obstetric emergency associated with substantial maternal and neonatal morbidity and mortality. Although systemic inflammation and vascular dysfunction have been implicated in its pathophysiology, the clinical and laboratory factors associated with PA remain incompletely characterized. In this study, we aimed to investigate the relationship between PA and first-trimester and preoperative laboratory parameters, along with selected clinical features.Methods: This retrospective case control study included 308 singleton pregnancies, comprising 59 women with PA and 249 controls. Maternal demographic characteristics, obstetric variables, laboratory parameters, hemodynamic measurements, and maternal and perinatal outcomes were compared between groups. Factors independently associated with PA were identified using multivariable logistic regression analysis. Results: Compared with controls, females with PA had lower gestational age at delivery and neonatal birth weight (both p

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