Cleft Alveolar Bone Grafting Using Mandibular Symphyseal Bone Graft and Resorbable Collagen Membrane: A CBCT-Based 3-Dimensional Morphometric Analysis
Andi Setiawan Budihardja, Dimas Satria Putra, Lia Hapsari AndayaniObjective
Iliac cancellous bone graft has been regarded as the gold standard for secondary alveolar bone grafting (SABG); however, it is associated with a high resorption rate and donor-site morbidity. This study aimed to evaluate the radiographic outcomes of SABG using a mandibular symphyseal bone graft combined with a double-layer resorbable collagen membrane through standardized 3-dimensional cone-beam computed tomography (CBCT)–based morphometric assessment.
Design
Retrospective study.
Setting
Patients with unilateral cleft lip/palate (UCLP) or bilateral CL/P (BCLP) who underwent SABG at a single center.
Patients and Intervention
Eighteen patients with UCLP/BCLP who underwent SABG using a mandibular symphyseal bone graft and a double-layer resorbable collagen membrane between 2022 and 2025.
Main Outcome Measures
Preoperative and 1.5-year postoperative CBCT-based 3-dimensional linear morphometric measurements, including cleft width reduction and postoperative bone bridge thickness.
Results
At 1.5 years postoperatively, cleft width significantly reduced at all measurement levels (
Conclusions
Mandibular symphyseal bone grafting combined with a double-layer resorbable collagen membrane yielded favorable radiographic outcomes, with substantial reduction of alveolar cleft defects and satisfactory bone bridge formation in this retrospective cohort. This technique may be a viable treatment option for selected patients. However, prospective controlled studies with larger cohorts and longer follow-up are needed to confirm its comparative effectiveness and long-term stability.