D. Bougle, F. Bureau, G. Deschrevel, C. Hecquard, D. Neuville, M. Drosdowsky, J. F. Duhamel

Chromium and Parenteral Nutrition in Children

  • Gastroenterology
  • Pediatrics, Perinatology and Child Health
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SummaryChromium (Cr) dosage was assayed in i.v. nutrition, serum, and losses of five children on total parenteral nutrition for 4 weeks. The Cr supply (4.7 ± 1.2 μUg/kg/day) was above recommended levels (0.5 μUg/kg/day). Serum (18.2 ± 1.8 μUg/L) and urine (37.4 ± 10.5 μUg/L) were also higher than control values (0.7–0.9 μUg/L and 0.2–0.8 μUg/L, respectively). Serum and urine Cr concentrations displayed a positive correlation. Serum Cr and Fc showed a negative correlation. These results confirm the potential toxicity of Cr previously reported in animals. Cr levels of i.v. nutrition solutes should be checked thoroughly.

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