DOI: 10.1039/d6ma01075j ISSN: 2633-5409

Chondrogenic differentiation of mesenchymal stromal cells in porous alginate hydrogels through spheroid formation

Mingxin Zhang, Huajian Chen, Tianjiao Zeng, Bowu Peng, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen

Porous alginate hydrogels control MSC distribution within the matrix and micropores. Spheroid-associated cell–cell interactions support chondrogenic differentiation without exogenous TGF-β supplementation.

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