Childhood Obesity as a Presenting Feature of Laurence–Moon–Biedl Syndrome: A Rare Case Report

Abstract

Laurence–Moon–Biedl Syndrome (LMBS) is a rare autosomal recessive ciliopathy characterized by a spectrum of clinical features, including obesity, polydactyly, hypogonadism, intellectual disability, retinal dystrophy, and renal anomalies. Here, we report the case of a 7-year-old boy of consanguineous parents, who presented with developmental delay, progressive obesity, visual impairment, intellectual disability, and polydactyly. Clinical evaluation revealed classical features of LMBS. Ophthalmologic findings showed reduced visual acuity with unilateral temporal pallor. Psychological assessment indicated mild intellectual impairment.