DOI: 10.1002/slct.202301535 ISSN:
C‐Heteroatom Bond Formation via a Highly C2‐Site Selective Functionalization of Quinone Imine Ketals
Xingxiu Nong, Linxia Li, Mengting Zhou, Teng Liu- General Chemistry
Abstract
Quinone imine ketals (QIKs), as a kind of functionalized organic synthons, have attracted considerable attention in organic synthesis during recent years. In this paper, acetyl chloride, acetyl bromide, H‐phosphonate and thiophenol were used as nucleophiles to react with QIKs, providing a series of C2‐site functionalization molecules via an efficient C−Cl/C−Br/C−P/C−S bond formation with high yields and excellent selectivity under mild conditions.