Outline
DOI: 10.1039/d6ob01552b ISSN: 1477-0520
Chemoselective aryllithium addition to an α-cyanoester under continuous-flow conditions
Mohmmad S. Qenawy, Xianzhu Zhong, Aiichiro NagakiChemoselective addition of aryllithium reagents to an α-cyanoester was achieved under continuous-flow conditions, enabling selective ester-to-ketone conversion while retaining the nitrile group.
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