DOI: 10.1039/d6fo02950g ISSN: 2042-6496
Chemical characterization and urate-related activities of constituents of Paeonia lactiflora : 1,2,3,4,6- O -pentagalloylglucose inhibits xanthine oxidase a
Ruoling Xu, Tingting Jin, Jingwen Wang, Ting Ji, Fucai Ren, Ning LiPhytochemical profiling of Paeonia lactiflora identified two representative urate-related constituents: PGG inhibited xanthine oxidase (IC 50 8.11 μM), whereas paeoniflorin protected HK-2 cells and regulated URAT1, GLUT9, OAT1 and ABCG2.