Outline
DOI: 10.1152/ajpcell.00374.2026 ISSN: 0363-6143
Characterization of von Willebrand factor-enriched extracellular vesicles and their association with platelet adhesion in COVID-19
Ling Chen, Aatish Mahajan, Anil Kumar Ram, Prabhakar Chalise, Quan Zhang, Huan Dong, Zhijian Wu, Liang Zheng, X. Long Zheng, Leslie Spikes, Navneet Kaur DhillonCirculating small extracellular vesicles in patients with COVID-19 carrying ultra-large VWF multimers boost platelet adhesion and activate endothelial cells, highlighting a potential driver and biomarker of COVID-19-associated coagulopathy.
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