C−H Functionalization of Quinoxalines

As a powerful tool in modern organic synthesis, C–H functionalization offers an elegant shortcut to molecular complexity, which enables direct bond transformations without any pre-functionalization. In this connection, C−H functionalization of quinoxalines offers a direct and efficient approach to modify the quinoxaline scaffold, a key structural motif in biologically active compounds and materials. This personal account describes the methodologies developed by our group for C−H activation and functionalization of quinoxaline compounds.