CATEGORIZATION OF SEROUS EFFUSIONS USING THE INTERNATIONAL SYSTEM FOR REPORTING SEROUS FLUID CYTOPATHOLOGY AND ASSESSMENT OF RISK OF MALIGNANCY WITH DIAGNOSTIC ACCURACY

Serous effusion cytology is a key diagnostic tool for evaluating pleural, peritoneal, and pericardial effusions. It is rapid, cost-effective, and minimally invasive, yet presents challenges, particularly in distinguishing malignant cells from reactive mesothelial cells due to overlapping features. The International System for Reporting Serous Fluid Cytopathology (ISRSFC) was recently introduced to address these challenges by standardizing reporting and enhancing risk stratication