DOI: 10.17567/currresdentsci.1594006 ISSN: 2822-2555

Burkitt's Lymphoma of the Mandible: A Rare Case Report with Intraoral Ultrasound Findings and Systematic Review

Nida Kuzey, Fatma Çağlayan, Kübra Törenek Ağırman, Zeynep Bayramoğlu, Sare Şipal
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Burkitt lymphoma (BL) is a rare and aggressive type of non-Hodgkin lymphoma, typically affecting younger individuals. Its occurrence in the mandible is exceedingly rare, posing significant challenges in diagnosis and treatment. This study presents a case of a rare mandibular BL and highlights the diagnostic value of intraoral ultrasonography (US) when compared to traditional imaging techniques. Furthermore, a systematic literature review of similar cases was conducted. A 19-year-old female patient presented to our clinic with rapidly progressing mandibular swelling and pain. Clinical and radiographic examinations, including CBCT, revealed the presence of an osteolytic lesion. Intraoral US was performed to assess the lesion's size, internal structure, and vascularization. Histopathological and immunohistochemical analyses confirmed the diagnosis of BL. Intraoral US revealed an iso-hypoechoic heterogeneous solid lesion with posterior bone destruction. The obtained ultrasonographic findings were consistent with histopathological examination. Additionally, a literature review identified 21 cases, the majority of which were male, with an average age of 19.5 ± 16.0 years. Mandibular BL is a rare and aggressive disease. Early diagnosis and the use of appropriate imaging techniques are critical for the success of treatment. This case demonstrates that intraoral US is an effective method for pre-diagnosing rare intraoral malignancies such as BL. Intraoral US played a significant role in evaluating bone destruction and the internal structure of the lesion, thereby enhancing diagnostic accuracy. These findings underscore the value of intraoral US as a valuable tool in the early diagnosis and management of BL.Keywords: Burkitt’s lymphoma, CBCT, mandible, ultrasound

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