Dianna Yanchis, Stephanie So, Catherine Patterson, Christina Belza, Elizabeth Garofalo, Sylvia Wong-Sterling, Carina Silva, Yaron Avitzur, Paul W. Wales, Jessie M. Hulst, Dehan Kong, Libai Xu, Yuxuan Li, Glenda Courtney-Martin

Body Composition and Physical Activity in Pediatric Intestinal Failure On and Off Parenteral Nutrition

  • Gastroenterology
  • Pediatrics, Perinatology and Child Health
Save to CiteDrive Show PDF

Objectives: Data on the relationship between body composition (BC) and physical activity (PA) in children with intestinal failure (IF) are lacking. The objectives were to collect data on PA and BC in children with IF, both parenterally and enterally fed, and to assess the relationship between PA and BC. Methods: Cross-sectional study in children 5–18 years with IF including those receiving parenteral nutrition (PN) and those fully enterally fed. PA levels were measured using accelerometry. BC was measured by dual-energy X-ray absorptiometry. Data were compared to age- and sex-matched population norms using t tests. Regression analysis assessed the relationship between BC and PA. Results: Fifty-eight children with IF (38 males), mean (SD) age of 10.0 (3.5) years, 20 dependent on PN were included. Patients with IF had significantly fewer steps per day (P ≤ 0.001) compared with literature controls, with a mean (SD) of 7,972 (3,008) and 11,749 (1,106), respectively. There were no significant differences between patients receiving PN and those enterally fed, but both groups were significantly less active than literature controls (P < 0.001). Patients with IF had higher fat mass and lower fat-free mass compared to literature controls (P = 0.008). PA had a significant effect on BC (r 2 = 0.32, P < 0.001). Conclusions: Children with IF, those receiving PN and those fully enterally fed, are at risk of decreased PA and altered BC. PA should be part of ongoing rehabilitation and management to optimize outcomes.

Need a simple solution for managing your BibTeX entries? Explore CiteDrive!

  • Web-based, modern reference management
  • Collaborate and share with fellow researchers
  • Integration with Overleaf
  • Comprehensive BibTeX/BibLaTeX support
  • Save articles and websites directly from your browser
  • Search for new articles from a database of tens of millions of references
Try out CiteDrive

More from our Archive