DOI: 10.1039/d6cb00206d ISSN: 2633-0679
BODIPY-tagged β-lactams as selective quenched activity-based probes to target human neutrophil elastase
Rita Felix, Luís Carvalho, Ismael Rufino, Rita Guedes, Ana Margarida Madureira, Ana Mallo-Abreu, Lídia Gonçalves, Olga Genilloud, Rosario Fernandez-Godino, Maria C. Ramos, Rui MoreiraBODIPY-tagged quenched activity-based probes enable selective detection of active human neutrophil elastase with low background fluorescence and enhanced imaging performance.