DOI: 10.1039/d6sc04815c ISSN: 2041-6520
Biosynthesis of (+)-palitantin requires homologs of alkyl salicylaldehyde-forming enzymes without involvement of an aromatic intermediate
Rui Ge, Zheng-Xi Zhang, Li Yang, Li-Dan Pang, Shu-Ming LiAlkyl salicylaldehyde-forming enzyme homologs in the biosynthetic pathway of (+)-palitantin in Penicillium palitans assemble a non-aromatic skeleton for subsequent stereo controlled modifications by three oxidoreductases.