DOI: 10.1097/prs.0000000000013240 ISSN: 0032-1052

Biologic Matrices and Synthetic Meshes in Breast Aesthetic and Reconstructive Surgery

Neil Tanna, Isabelle T. Smith, Evan Rothchild, Gabrielle Odoom, Ben H. Zhang

Learning Objectives:

After studying this article, the participant should be able to: 1. Describe the types, structural characteristics, and clinical indications for biologic matrices and synthetic meshes used in breast aesthetic and reconstructive surgery. 2. Evaluate the evidence on clinical outcomes, complication profiles, and aesthetic results associated with each material. 3. Apply key principles of material selection based on patient-specific factors, procedural context, and surgical goals.

Summary:

This article reviews the role of biologic matrices and synthetic meshes in breast aesthetic and reconstructive surgery. It discusses material composition, surgical applications, and emerging roles in aesthetic operations such as augmentation, mastopexy, and reduction. The authors compare complication rates, capsular contracture prevention, and aesthetic outcomes associated with each material type, highlighting differences in safety, cost-effectiveness, and long-term performance. Evidence-based data are presented to guide decision-making and improve patient outcomes, while acknowledging current limitations in the literature and opportunities for further investigation.