DOI: 10.36718/1819-4036-2026-8-177-186 ISSN: 1819-4036

BIOCHEMICAL PARAMETERS OF BLOOD AND QUALITY ASSESSMENT OF COW EMBRYOS USING OXIPROTECT IN THE SUPEROVULATION SCHEME

Yuliya Gorbacheva, Elena Kuz'minova, Danila Kopylov

The aim of the study is to investigate the effect of Oxyprotect, included in the donor cow superovulation regimen, on serum biochemistry parameters and the quality of the resulting embryos. The study was conducted at an agro-industrial enterprise located in the flat part of the Azov-Kuban Lowland in 2024. The subject of the study was the multifunctional Oxyprotect, developed in the Pharmacology Department of the Kazan Scientific Center for Veterinary Medicine. The research included optimizing the donor cow superovulation regimen using the new vitamin and mineral supplement Oxyprotect, comparing serum biochemistry parameters, and assessing embryo quality. The study involved Holstein cows, divided into two groups of 15 animals each using the paired analog method. After hormonal treatment, three artificial inseminations, and embryo washout, the donor cows were evaluated for embryos and their serum biochemistry was analyzed. Based on the results of the work, during the laboratory evaluation of embryos with ranking by groups, they were assigned the following categories: 1st category in the experimental group – 62 (54.9 %) and in the control – 57 (56.4 %); 2nd category in the experimental group – 35 (31 %) and in the control – 31 (30.7 %); in the experimental group there were no unfertilized eggs, and in the control group their number was 2 pcs. After the use of Oxyprotect in donor cows, blood biochemistry analysis showed an increase in: glucose – by 15.5 %; total protein – by 7; cholesterol – by 19.5; total calcium – by 9.2; inorganic phosphorus – by 14.3 and magnesium – by 13.3 %, – with a decrease in the concentration of ALT – by 13.9 % and cortisol – by 12.6 % relative to the control group. Oxyprotect stimulates metabolic processes, activates energy and mineral metabolism, stabilizes liver structure, and reduces the effects of stress. Improved blood biochemistry positively impacts the quality of the resulting embryos.