DOI: 10.4103/jmr.jmr_43_26 ISSN: 3051-0546

Bibliometric Analysis of Platelet-Rich Plasma Applications in Thin Endometrium and Recurrent Implantation Failure: Research Trends, Thematic Clusters, and Collaborative Patterns (2000–2025)

Sureyya Saridas Demir, Bulent Demir
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Abstract

Background:

Thin endometrium and recurrent implantation failure (RIF) are among the most refractory challenges in assisted reproductive technology. Autologous platelet-rich plasma (PRP) has emerged as a promising regenerative intervention; however, the global structure of this rapidly expanding research field has not been systematically mapped.

Aims and Objectives:

The aim of this study was to characterize the bibliometric landscape of PRP research in thin endometrium and RIF; identify the most productive countries, journals, and authors; delineate thematic clusters; and trace temporal research trends over the period 2000–2025.

Materials and Methods:

A Title-field search of Web of Science (WoS; n = 473) and Scopus ( n = 86, after excluding 3 errata/unrelated records) was conducted in June 2025. After DOI-based deduplication removed 62 overlapping records, 24 Scopus-unique documents were added to the WoS dataset, yielding 497 documents. Bradford’s Law, Lotka’s Law, keyword co-occurrence networks, and country coauthorship networks were computed with Python 3.10.

Results:

Of 497 documents, 93% were published from 2015 onward, with 91 publications recorded by the June 2025 search date. Original articles (62.0%) and reviews (23.3%) dominated. Human Reproduction ( n  = 29) and Fertility and Sterility ( n  = 28) were the most productive journals; Bradford’s Law identified a four-journal core. China led the country output ( n  = 112), followed by the USA (56), India (50), and Iran (45). Seven thematic clusters were identified. Among the WoS-indexed records, the total citations were 8498 and the h-index was 50.

Conclusion:

PRP research in thin endometrium and RIF has expanded exponentially since 2015 but remains geographically concentrated and dominated by small single-center studies. Multicenter randomized controlled trials with standardized protocols and live birth as the primary endpoint are urgently needed.

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