DOI: 10.1177/01455613261499466 ISSN: 0145-5613
Beyond Hoarseness: Primary Low-Grade B-Cell Lymphoproliferative Disorder of the Supraglottis
Steven Alvarado, Anna P. HsuWhile squamous cell carcinoma represents the majority of malignant laryngeal tumors, primary laryngeal lymphoma is exceptionally rare. We present the case of a 78-year-old female with a history of sarcoidosis and remote tobacco use who presented with progressive hoarseness and throat discomfort. Imaging revealed a left supraglottic mass with associated cervical lymphadenopathy. Histopathologic evaluation demonstrated a low-grade B-cell lymphoproliferative disorder involving the supraglottis. This case highlights the importance of maintaining a broad differential diagnosis for persistent dysphonia and underscores the critical role of tissue biopsy in distinguishing malignant lymphoid processes from inflammatory or epithelial pathologies.