Behavioral Variant Frontotemporal Dementia With the Dominantly Affected Caudate Nucleus in 18F-FP-CIT PET/CT

Abstract

Frontotemporal dementia is a clinical syndrome that is characterized by a progressive deterioration in behavior, personality, and/or language, with relative preservation of memory, and its phenotype and molecular basis are heterogeneous. We present a case of a 62-year-old female patient who underwent ¹⁸F-FDG PET/CT and ¹⁸F-FP-CIT PET/CT for differential diagnosis of psychiatric disease and types of dementia. ¹⁸F-FDG PET/CT image showed a compatible finding for frontotemporal dementia, and ¹⁸F-FP-CIT PET/CT image showed dominantly decreased dopamine transporter activity in the bilateral caudate nucleus.