BACTERIOLOGICALAND CLINICAL PROFILES OF PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIAAT A TERTIARY CARE CENTRE IN NORTHERN INDIA

Introduction: Pneumonia, characterized by acute lung inammation, can result from infectious or non-infectious factors and ranks as a leading infectious disease-related cause of death in the United States. Globally, lower respiratory tract infections, including community-acquired pneumonia (CAP), contribute signicantly to disease burden, with India shouldering a substantial portion. Bacterial proles of CAP exhibit geographical and temporal variation, inuenced by antibiotic use, environmental factors, and disease awareness. This study aims to analyze the clinical and bacteriological characteristics of CAP in a North Indian tertiary care center. Objective: To analyze the bacteriological and clinical characteristics of individuals diagnosed with community-acquired pneumonia at a tertiary care center in Northern India. Methods: A crosssectional study included 100 diverse CAP patients, with data collected on demographics, clinical symptoms, comorbidities, and antibiotic sensitivity. Laboratory assessments comprised blood cultures, sputum samples, and radiological evaluations. Statistical analysis determined associations between clinical features and bacteriological ndings, with ethical guidelines followed. Results: Most patients were male (55%) with hypertension (30%) as a common comorbidity. Streptococcus pneumoniae was the predominant pathogen (35%), and typical symptoms included cough (95%) and fever (90%). Antibiotic sensitivity varied, with Vancomycin exhibiting the highest sensitivity at 90%. Conclusion: This study reveals key insights into CAP in Northern India, emphasizing the predominance of Streptococcus pneumoniae, common clinical symptoms, and varying antibiotic sensitivities. Understanding local CAP proles is crucial for effective management and guideline adherence during exacerbations.