DOI: 10.1039/d6np00017g ISSN: 0265-0568

Bacterial cytological profiling for mode-of-action discovery of natural product-derived antibiotics: progress, challenges, and future directions

Poochit Nonejuie, Thanadon Samernate, Filosofia F. T. A. Prasasti, Vorrapon Chaikeeratisak, Joe Pogliano

Bacterial cytological profiling reveals antibiotic mechanisms via single-cell morphology analysis. This review examines its applications, limitations, practical implementation, and future directions for natural product-derived antibiotic discovery.

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