Drug-induced exfoliative dermatitis also known as erythroderma is a group of rare and severe drug hypersensitivity reactions involving skin and usually occurring from days to several weeks after drug exposure. Cutaneous drug eruptions are one of the most common types of adverse reactions to medications. Although the etiology is often unknown, exfoliative dermatitis may be the result of a drug reaction or underlying malignancy. In Ayurveda, this clinical entity can be correlated with Raksa(~skin disease). Acharya Sushruta has described Raksa as Ksudra kustha and also as a Ksudra roga having dominance of Kapha dosha with clinical representation of eruptions with pruritis. The word “Kustha”(~skin disease) is used in Ayurveda generally as a universal term for all types of skin disorders or manifestations. Kustha is a Tridoshaja vyadhi mentioned in Ayurveda that undergoes manifestation in the Bahya rogamarga. Here we represent a case of 36-yr old female patient complaining of reddish patches over left and right hypochondriac region with intense itching and burning sensation that has been treated successfully with Rasa manikya, Prawal pishti, Kaishore guggulu, Avipattikar churna, Maha manjisthadi kashyam for 15 days of regular treatment. The present case report illustrates the signicance of Shamana chikitsa in the management of Raksa.

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