DOI: 10.1039/d3sc02705h ISSN:
Axially chiral styrene-based organocatalysts and their application in asymmetric cascade Michael/cyclization reaction
Yu Hao, Zi-Hao Li, Zhi-Gang Ma, Ru-Xin Liu, Rui-Tian Ge, Quan-Zhe Li, Tong-Mei Ding, Shu-Yu Zhang- General Chemistry
A series of axially chiral styrene-based organocatalysts were designed, synthesized, and applied in asymmetric cascade Michael/cyclization reactions. These catalysts controlled the stereoselectivities through π–π interactions and multiple H-bonds.