DOI: 10.4103/ijnm.ijnm_26_23 ISSN: 0972-3919

Autoimmune Encephalitis as a Rare Paraneoplastic Syndrome in Adrenocortical Carcinoma

Debabrata Mohapatra, Madhavi Tripathi, Sakshi Ojha, Jagdish Prasad Meena, Biswaroop Chakrabarty
  • Radiology, Nuclear Medicine and imaging

Paraneoplastic neurologic syndromes (PNSs) are rare in pediatrics and are understood to be consequences of cross-reactivity against various neuroendocrine antigens expressed on cancer cells. Here, we report a case of autoimmune encephalitis, a type of PNS associated with a case of adrenocortical carcinoma (ACC), that had a clinical response to immunosuppressive therapy. ACC is a rare tumor with controversial tissue of origin but expresses various neuroendocrine antigens that could be the possible mechanism for this rare yet interesting association.

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