Atrial fibrillation and quality of life in patients with acute decompensation of chronic heart failure
M Danoon, V Tolkacheva, T Zhdanova, F Cabello-Montoya, Z H KobalavaAbstract
Aim
To study the parameters of quality of life in patients withatrial fibrillation (AF) depending on the heart failure (HF) phenotype and AF type.
Material and methods
A prospective cohort study included 151 patients with nonvalvular AF who were hospitalized with an acute decompensation of chronic HF (mean age 75 ± 9.38 years, 56%). All patients underwent the quality-of-life assessment using the Kansas (KCCQ-12) and Minnesota (MLHFQ) questionnaires, as well as Duke Activity Status Index (DASI) at admission.
Results
The incidence of paroxysmal AF was 23%, persistent AF– 19%, permanent AF- 58%. There were no significant differences in the parameters of quality of life according to the Kansas, Minnesota questionnaires and the DASI index depending on the HF phenotype. There were no significant differences between the groups of patients with paroxysmal and persistent forms of AF also. There was a significant decrease in the physical limitations (39,4 versus 43,3, p<0,05), symptoms(26,5 versus 32,7, p<0,01), functional status (27,4 versus 37,5,p<0,001) and clinical condition (29,2 versus 36,2, p<0,01)according to the Kansas questionnaire, as well as a significant deterioration of the quality of life (57,0 versus 50,8, p<0,05)according to the Minnesota questionnaire in patients with permanent AF in comparison with patients with paroxysmal/persistent AF respectively.
Conclusion
The presence of a permanent form of AF significantly worsens the quality of life of patients, unlike paroxysmal and persistent forms in patients with acute decompensation of chronic heart failure.