ASSOCIATION OF RENAL PROFILE PARAMETERS WITH TSH IN HYPOTHYROID PATIENTS

Background: Thyroid stimulating hormone (TSH) have a great impact on the kidneys as they monitor growth, development as well as hemodynamics by modulating the glomerular ltration rate and renal plasma ow. Objective: To correlate the renal prole parameters (serum urea, uric acid, creatinine, calcium, phosphorus, alkaline phosphatase, sodium, potassium, chloride and eGFR) with serum TSH in hypothyroid patients. Material and Methods: Automated methods were used for the evaluation of renal prole parameters, Modication of diet in renal disease (MDRD) formula for eGFR and ELFA method for serum TSH in the sample size of 150 hypothyroid patients. Result: TSH levels were found to have signicant correlation with several renal prole parameters including serum urea, creatinine, uric acid, calcium, phosphorus, sodium and eGFR. Conclusion: Renal prole test should be monitored in the patients of hypothyroidism for the proper diagnosis as well as to monitor the severity of the underlying cause.