Association of Quick of Blood on Leukocyte Levels in Patients with Chronic Kidney Disease Who Undergo Regular Hemodialysis: A Retrospective Study
Afna Amalia Ihsan, Yuli Hermansyah, Ayu Munawaroh Aziz, Rini Riyanti, Dion Krismashogi DharmawanIntroduction:
Increasing the number of patients with chronic kidney disease (CKD) affects the required hemodialysis, whereas their clinical condition is determined by the uremic toxin in the circulating blood. These conditions were one of the quick of blood (Qb) in the dialysis process, which regular hemodialysis may improve clinical outcomes. The study aimed to analyze the association of Qb on leukocyte levels in patients with CKD.
Methods:
The study used a retrospective design with consecutive sampling. The number of participants was 57 patients with CKD who experience regular hemodialysis twice weekly. Data analysis included Qb, leukocyte, lymphocyte, and neutrophil levels. Subsequently, the data analyzed were utilized with Spearman’s correlation, Pearson’s correlation, ANOVA, or Kruskal–Wallis’s tests, which were considered significant according to
Results:
The results show that the participants are aged 50–59 years (31.6%), female (64.9%), have a dialysis period 13–24 months (26.3%), and have vascular access in the form of arteriovenous Shunt (86%). The analysis shows negative moderate correlation between Qb and leukocyte levels with
Conclusion:
This study demonstrated a negative correlation between Qb and leukocyte levels in patients with CKD undergoing regular hemodialysis. In contrast, no correlation was observed between Qb and lymphocyte or neutrophil levels, highlighting the importance of monitoring Qb alongside leukocyte profiles to optimize hemodialysis adequacy.