Minoru Deguchi, Hiroki Homma, Kathleen Y. de Almeida, Ayumu Kozuma, Mika Saito, Yosuke Tsuchiya, Karina Kouzaki, Eisuke Ochi, Takanobu Okamoto, Koichi Nakazato, Naoki Kikuchi

Association of MMP3 gene polymorphism and sex on recovery of muscle strength after eccentric exercise

  • Physiology (medical)
  • Physiology

Sex differences were identified in the AUC of creatin kinase (CK) and interleukin 6 (IL-6) after eccentric exercise, both of which were greater in men. A genotype-sex interaction was identified in recovery of maximal voluntary contraction (MVC). The G allele showed a significantly lower recovery of MVC than AA genotype in men. To our knowledge, this is the first study to report the interaction between MMP3 gene rs522616 polymorphism and sex difference on recovery of muscle strength after eccentric exercise.

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