Association Between Hypomineralisation of Second Primary Molars and Tooth Agenesis
Débora Juliana de Araújo Lopes, Eloisa Cesario Fernandes, Jaderson Felipe Santos Dantas, Patrícia Bittencourt SantosABSTRACT
Background
Hypomineralisation of second primary molars (HSPM) is an enamel defect with a multifactorial and potentially genetic aetiology. While the association between enamel defects and dental anomalies is a relatively recent area of investigation, it has not yet been explored specifically in cases of HSPM.
Aim
To assess the association between HSPM and tooth agenesis (TA).
Design
A retrospective cross‐sectional study was performed using pre‐treatment records of patients aged 7–12 years. A total of 285 patient records were evaluated. Statistical analyses were performed using the Fisher's exact test and logistic regressions.
Results
A higher prevalence of TA was observed among children with HSPM‐affected teeth (95% CI: 1.07–3.17, φ ‐coefficient: 0.238, PR: 1.84). Individuals with severe HSPM had significantly greater odds of TA (OR = 12.47; p < 0.001; 95% CI: 3.47–24.70). Patients with HSPM had a significantly higher likelihood of experiencing TA (OR = 6.97), particularly second premolar agenesis (OR = 11.80; p < 0.001; 95% CI: 2.83–49.10).
Conclusion
An association was found between HSPM and TA, particularly involving mandibular second premolars. Moreover, increased HSPM severity was linked to a higher risk of developing TA.