Meryem-Nur Duman, Alexander Angeloski, Michael S. Johnson, Tristan Rawling

Aromatic long chain cations of amphiphilic ionic liquids permeabilise the inner mitochondrial membrane and induce mitochondrial dysfunction at cytotoxic concentrations

  • Pollution
  • Environmental Chemistry

Aromatic long chain cations of amphiphilic ionic liquids (AmILs) accumulate in and permeabilise the IMM at their cytotoxic concentrations. The AmILs depolarise IMM, inhibit oxidative phosphorylation and ATP synthesis, and induce ROS formation.

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