DOI: 10.1039/d6ra06478g ISSN: 2046-2069
AQbD-based development and validation of an HPLC–PDA method for simultaneous determination of sibutramine, desmethylsibutramine, and didesmethylsibutramine in herbal weight-loss supplements
Dao Thi Cam Minh, Le Anh Thi, Le Thi My Duyen, Nguyen Dang Thuy Anh, Nguyen Quang Hung, Pham Thi Thanh HaAn AQbD-optimized HPLC-PDA method was validated for screening illicit sibutramine and its metabolites in adulterated herbal weight-loss formulations.