Application of the International System for Reporting Serous Fluid Cytopathology in a Tertiary Care Center of North India
Mohd Rafey, Kafil Akhtar, Fatima Meraj, Murad Ahmed, Mohammad Jaseem HassanAbstract
Background and Aim:
The International System for Reporting Serous Fluid Cytopathology was designed to standardize the reporting of serous fluid cytology, which we have applied for the reporting of serous fluid cytology in the present study.
Materials and Methods:
This retrospective study was conducted in the Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, from February 1st, 2021, to March 31st, 2023, on 966 cytospin smears of serous body cavity fluids from pleural, peritoneal, and pericardial cavity. The effusion findings were examined for gross morphological details, stained with hematoxylin and eosin and Papanicolaou stains, and reported according to The International System for Reporting Serous Fluid Cytopathology.
Results:
On review, 101 (10.5%) cases were in the nondiagnostic category, 682 (72.6%) cases were negative for malignancy, 31 (3.2%) cases were of atypia of undetermined significance, 41 (4.2%) cases were suspicious for malignancy, and 111 (11.5%) cases were malignant.
Conclusion:
The International System for Reporting Serous Fluid cytology for reporting serous fluid cytology is feasible and helpful for clinical correlation; it reduces interobserver bias and ultimately improves diagnostic yield, reproducibility, and standardization of serous body fluid cytology.