Antibacterial coatings based on zinc oxide nanoparticles

Subject of study . Zinc oxide nanoparticle coatings are investigated. Aim of study . This work aims to develop an effective technology for producing antibacterial coatings using the laser-induced backward transfer method by optimizing the laser radiation and scanning system parameters. Method . The laser-induced backward transfer method is used to fabricate the coating. Optical and scanning electron microscopy are used to characterize the coating topography in conjunction with probe microscopy. Nanoparticle sizes are analyzed by dynamic light scattering. Main results . Depending on the transfer regime, both hydrophilic and hydrophobic coatings composed of zinc oxide nanoparticles with sizes ranging from 16 to 458 nm are obtained. The coatings exhibit antibacterial activity against the Gram-negative bacterium Pseudomonas aeruginosa. Investigation of bacterial viability using the LIVE/DEAD BacLight staining kit confirmed the results of microbiological culture analysis. Practical significance . Zinc oxide nanoparticle-based coatings may serve as a basis for the development of antibacterial agents against a wide range of pathogenic microorganisms.